Inn at Palmetto Bluff Bluffton, S.C.

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Located on a 20,000-acre tract called Palmetto Bluff, this Auberge resort (consistently named to Condé Nast Traveler's Gold List) extends from the headwaters of the May River near Bluffton, South Carolina (just thirty minutes north of Savannah), and into the heart of Carolina Lowcountry. Expect sleepy afternoons lounging on your cottage's screened porch, which overlooks the salt marsh (this is where you'll want to get up early and watch the sunrise). No cars are allowed in the cottage area, so ride into the adorable town center for breakfast on one of your cottage's bicycles. Fifty cottages and cottage suites start at $475 per night, and twenty-five two- to four-bedroom village rental homes start at $1,100 per night (palmettobluffresort.com).

Green Factors

The location of this exclusive, ultraluxurious boutique inn is what makes it so eco-conscious. Guests can experience the May River's coastal salt marsh full of wildlife on the two-hour kayak tour, where a naturalist serves as a guide and offers insight into the area's lush eco-system. Sign up for the Backcountry Discovery Dolphin Tour, where you can discover hidden creeks and undeveloped islands and see dolphins and other wildlife, while leaving their natural habitat undisturbed.

Save the World

Palmetto Bluff combines history with an eco-friendly twist during the Outback Boat Tour and Archaeological Paddle. As you make your way to Page Island, you'll explore coastal marshlands, tidal creeks, and ancient Indian cultural sites.